Pharmaceuticals in Thoughts from the Centre

The Year Ahead: the public health impact of COVID-19

By Karen Taylor, Director, Deloitte Centre for Health Solutions

Deloitte-uk-cfhs-blog-jan-15

Earlier this week I joined my fellow Insight Leads as a panellist on a Deloitte Academy virtual event discussing ‘The Year Ahead’.1 My remit was to discuss the current extent and mitigations of the COVID-19 pandemic, and how the next 12 months might unfold. Unfortunately, the past month has seen a sharp rise in cases across many countries and the introduction of more severe restrictions. In the UK we have seen the continued escalation in the number of people testing positive, the NHS under more intense pressure than at any other time during the pandemic. The UK has also seen the rollout of two approved vaccines and a third national lockdown. My expectations for the year ahead reflect this increasingly complex and rapidly evolving situation and the developments likely to affect public health during 2021.

Continue reading

Posted on 15/01/2021 | 0 Comments

Healthcare and life sciences unmasked: A future accelerated by COVID-19

By Karen Taylor, Director, Deloitte Centre for Health Solutions

Wheel-blog

Over the last few weeks of 2020 we published a series of ten predictions on what the future of healthcare and life sciences looks like in 2025. Each prediction follows the same format, including a number of ‘portraits’ imagining the experience of individuals and organisations in 2025, the evidence today that enables us to predict tomorrow and the common constraints that need to be overcome to realise the prediction. We also considered how the COVID-19 pandemic has affected each prediction. Subsequently, we brought all of the predictions together in one report: The future unmasked: Predicting the future of healthcare and life sciences in 2025 and launched a podcast with senior leaders from our life sciences and healthcare practice discussing how the predictions affect their parts of the industry. I have used this first blog of 2021 to examine the cross cutting constraints that need to be overcome to realise our view of the future.

Continue reading

Posted on 08/01/2021 | 0 Comments

The future unmasked: conscious care and greater collaboration

By Karen Taylor, Samrina Bhatti and Krissie Ferris, Deloitte Centre for Health Solutions

Wheel-blog

This is the last week in the staggered launch of the final two predictions in our report ‘The future unmasked: Predicting the future of healthcare and life sciences in 2025’. Our predictions: ‘Healthcare and life sciences companies have prioritised decarbonisation’, and ‘Clusters of trusted partnerships have accelerated innovation’ explore two crucial developments in the evolving relationship between the stakeholders in the health ecosystem. These are the increased priority companies are giving to reducing their carbon footprints and the growth in trusted partnerships and collaborations between stakeholders. We also examine the impact that the COVID-19 pandemic has had in accelerating the pace of change.

Continue reading

Posted on 11/12/2020 | 0 Comments

The future unmasked: digitally transformed pharma R&D and supply chains

By Karen Taylor, Samrina Bhatti and Krissie Ferris, Deloitte Centre for Health Solutions

Wheel-blog

This is week four in the phased launch of the ten predictions in our report ‘The future unmasked: Predicting the future of healthcare and life sciences in 2025’. Each prediction is brought to life by imagining what the experience of individuals might look like in 2025, examples of the evidence today to predict tomorrow, and considers the impact that the COVID-19 pandemic has on each prediction. These two predictions we have launched this week are focussed on two crucial parts of the biopharma value chain: prediction seven ‘Companies have reversed the decline in the returns from pharma R&D’, and prediction eight ‘Next generation supply chains are integrated into healthcare and the patient experience’.

Continue reading

Posted on 04/12/2020 | 0 Comments

Vaccines like it (very) cold – how to build a resilient COVID-19 vaccine supply chain

By Maria João Cruz, PhD, Research Analyst, Centre for Health Solutions, and Jose M. Suárez, Manager, Life Sciences Advisory

Vaccine-supply-chain

The COVID-19 pandemic has claimed over 1.1 million lives and infected over 45 million people worldwide, numbers that continue to increase.1 Alongside its devastating human impact, the pandemic has exerted unrelenting pressure on pharma and healthcare supply chains. COVID-19 has exposed the fragility of our medical supply chains, and highlighted their global inter-dependencies and vulnerability to shock. We have also experienced major challenges in the medical equipment supply chain, including manufacturing, transport and distribution of testing kits, personal protective equipment (PPE), and ventilators. However, these challenges pale in comparison to the huge task ahead of us in getting life-saving COVID-19 vaccines to people around the world, in record time, to halt the spread of this virus. Importantly, this will have to be done while maintaining production, distribution and administration of other life-saving therapies, including the seasonal flu shots, and other essential medicinal products.

Continue reading

Posted on 30/10/2020 | 0 Comments

Diversity and inclusion in clinical trials – an imperative, especially in times of COVID-19

By Maria João Cruz, PhD, Research Analyst, Centre for Health Solutions

Covid-purple

Clinical trials provide the necessary evidence to prove safety and efficacy of new treatments and medical products. Given that the responses to a specific medication may differ among population subgroups depending on factors such as age, sex, genetic profile and ethnicity, clinical trials need to reflect the demographic diversity of the population that a pharma product is intended to serve.1,2 Last August the Centre published a blog on the importance of inclusion and diversity in clinical trials and why it should be a research priority. At the time, we highlighted the initiatives being launched by regulatory bodies to improve diversity in clinical research but noted that, while there have been some improvements, pharma companies were still struggling to enrol participants from diverse demographic groups, particularly women, racial and ethnic minorities, and the elderly.3

Continue reading

Posted on 09/10/2020 | 0 Comments

The Indian pharmaceutical industry: A bright future awaits?

By Pratik Avhad, Senior Analyst, Insight

Indian-pharma

Over the past months, our first blog in our series on the Indian pharma industry explored how the industry became the ‘pharmacy of the world’. Our second blog ‘the time of transition’ explored some of the new initiatives that the industry has embarked on to kick-start growth and tackle the stagnation and growth volatility that it has experienced over the past decade. However, some of these initiatives have been undermined by the health challenges and economic impact due to the COVID-19 pandemic. In this third blog of the series, I explore what the likely future looks like for this critically important industry.

Continue reading

Posted on 01/10/2020 | 0 Comments

Wake me up when September ends: my reflections on the search for a treatment for Alzheimer’s disease, in honour of World Alzheimer’s Month

By Dr Francesca Properzi, PhD. Research Manager, Centre for Health Solutions

Deloitte-uk-intelligent-drug-discovery

Since 2012, September has been celebrated as World Alzheimer’s Month, and this year’s theme is 'Let's talk about dementia'. This is clearly much needed, especially as one person is diagnosed with dementia every three seconds.1 As a neuroscientist, I spent more than 10 years leading a research lab dedicated to finding new approaches for diagnosing and treating neurodegenerative diseases at the Italian Institute of Health in Rome. I also had first-hand experience of the disease, as I had originally accepted that position and left my job in London, to take care of my father, who was himself fighting dementia. Those years have shaped me greatly both personally and professionally and, as September coincides with my last month at the Deloitte Centre for Health Solutions, I am delighted to use this blog to provide my reflections on the challenges presented by Alzheimer’s disease and to consider what more needs to be done to expedite progress in identifying treatments and ultimately a cure.

Continue reading

Posted on 25/09/2020 | 0 Comments

Boosting COVID-19 vaccination rates for the hesitant

By Sarah Thomas, managing director, Deloitte Center for Health Solutions, Deloitte Services LP, and Greg Szwartz, managing director, Life Sciences data science practice lead, Deloitte Consulting LLP

Covid

This week we are sharing a blog written by our US colleagues, Sarah Thomas, the managing director of Deloitte’s US Center for Health Solutions, and Greg Szwartz, who leads the life sciences data science practice for Deloitte Consulting LLP. The focus of their blog is on ‘vaccine hesitancy’ and the finding from surveys that show that 25 to 50 per cent of Americans have said they would be hesitant to get a COVID-19 vaccination due to concerns about safety and the unprecedented speed of development. In the UK, a survey by Ipsos MORI and King’s College London found that 53 per cent of respondents said they would certainly or very likely get a vaccine against COVID-19, and 16 per cent that they are unlikely to, or definitely will not, get the vaccine.1 We believe that the strategies and tactics identified in the US blog to help improve understanding of behaviours and increase uptake of inoculations are relevant to the UK and indeed to most countries.

Continue reading

Posted on 04/09/2020 | 0 Comments

COVID-19 vaccines: a closer look at the front runners

By Maria João Cruz, PhD, Research Analyst, Centre for Health Solutions

Covid-yellow

In early May, we published a blog about the race for a COVID-19 vaccine.1 At the time, biotech and biopharma companies together with research organisations and academia had commenced the development of some 110 potential vaccines against SARS-CoV-2. Notable features of the race include the unprecedented acceleration in the pace of R&D and the significant scale of collaboration and cooperation between stakeholders across multiple geographies.2 By the end of August, there are 203 vaccine candidates under development. Six have already reached Phase III or II/III clinical trials, the last stage of clinical development before vaccines can obtain regulatory approval (see Figure 1).3,4 This was achieved in only few months, rather than the years it would normally take.5 Importantly, the COVID-19 vaccine developers are using a variety of technologies and techniques, ranging from the tried and tested to completely novel approaches. This blog explores the different approaches being used for obtaining an approved and licenced vaccine.

Continue reading

Posted on 28/08/2020 | 0 Comments